Evidence Synthesis Program (ESP) - Durham Center of Innovation to ADAPT
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Durham Center of Innovation to ADAPT


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Evidence Synthesis Program (ESP)


Evidence Synthesis Graphic ADAPT website by Courtni France
The Durham H S R and D is one of six Evidence Synthesis Program Locations.  Our E S P is co-directed by Dr. Karen Goldstein and Dr. Jennifer Geer sh
The Durham ESP has a major training mission, collaborating with over 200 students, fellows, and junior faculty in the past 10 years.
We prioritize evidence syntheses that supports: clinical practice guidelines, implementation of evidence-based practices, setting directions for future research to address gaps in knowledge, identifying the evidence to support VA performance measures, and rationalizing drug formulary decisions.
VA partners and stakeholders include: mental health services, pharmacy, health promotion, health equity, patient centered care, women’s health, and research and development.
We collaborate with nominating stakeholders, national technical experts, content experts, clinician scientist, and health researchers to complete each evidence synthesis projects.


The Durham VA Evidence Synthesis Program was formed in 2009 to support high quality, rapid turnaround evidence syntheses to inform VA clinical and policy decisions. Durham is one of four VA ESP Centers across the country excluding the Evidence Synthesis Coordinating Office. The Center generates three evidence syntheses for the VA annually with a focus on topics nominated by VA policymakers and clinical leadership.

Durham VA and Duke clinical investigators, clinical fellows, postdoctoral fellows, and chief residents participate in evidence syntheses tailored for policymakers. By participating ESP, investigators learn systematic review methodology and have the opportunity to be a part of high impact publications (e.g., Annals of Internal Medicine), national/international presentations, and data briefing to VA leadership. 

Durham ESP Leadership:
Jennifer Gierisch, PhD (Co-Director)
Karen Goldstein, MD, MSPH (Co-Director)

Durham ESP Staff:
John W. Williams Jr, MD, MHS
 (Scientific Advisor)
Adelaide Gordon, MPH (Program Coordinator)
Belinda Ear, MPH (Research Health Science Specialist)

The Center is also supported by:
Liz Wing, MA (Medical Editor)
Andrzej Kosinski, PhD (Statistician)
Sarah Cantrell, MLIS (Medical Librarian)

The Durham ESP can generate a variety of products that can be completed in 12 months or less and includes:

  • Traditional systematic reviews.
  • Update of prior high quality systematic review(s) with a focus on relevance to VA.
  • Evidence brief responding to stakeholders need for rapid, evidence based summaries on an issue of high importance.
  • Review of reviews – synthesizing across multiple reviews on a topic.
  • Evidence mapping – mapping the epidemiology of existing research across a broad set of questions.

To view all ESP published reports or to nominate a topic please visit: 

Fiscal Year Reports by Courtni France